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Introduction and Background While significant progress has been made in the field of cocrystals, relatively few methods are available to prepare cocrystals. Traditional methods include crystallization from solution1, solvent-assisted grinding2, Kofler contact method3, and reaction [...]
Abstract / Introduction Cocrystals of pharmaceutical or nutraceutical molecules are considered challenging compounds to scale up by solution crystallization due to the possibility of incongruent dissolution of the components, which can lead to the crystallization [...]
Purpose The characterization of dissolution and solubility for an oral dosage form is of significance to the development and optimization of drug delivery, especially for BCS Class II and IV drugs of low solubility, where [...]