Chapter 1: Introduction to Solids Processing.
Powders-A Unique State of Matter? - Adhesion/Cohesion between Solid Surfaces - Mechanical Properties - Fracture Mechanics - Time-Dependent Deformation - Powder Flow and Tablet Compression
Chapter 2: Interparticle Forces: Attraction and Repulsion at Solid-Solid Interfaces of Organic Materials.
Background - London Dispersion Forces between Atoms and Particles - The Influence of Adsorbed Layers on Dispersion Forces - Forces between Atoms in Solution - Forces at Interfaces - Electrostatic Attraction - Forces Acting at Solid-Solid Interfaces of Organic Materials - Role of Surface Forces in Powder Beds and Compacts - References - Additional Reading
Chapter 3: Mechanical Behavior of Solids: Elements for Powder Beds and Compacts.
Fundamentals - Strength - Viscoelasticity - The Bonding Index - Stress Concentration and the Brittle Fracture Index - Mechanical Properties and the Force between Two Particles - Conclusions - References - Additional Reading - Glossary
Chapter 4: Powders.
Particle Size - Flowability, Simple Methods - Flowability, Shear Cell Evaluations - References
Chapter 5: Size Enlargement by Wet Massing and Drying.
The Benefits from Granulation - The Influence of Processing Method - The Forces to Produce Wet Massing - Dynamic Effects, Tack - The Strength of Aggregates - Capillary Held Liquid and Measured Strength of Granules - Pharmaceutical Process Control - Drying of Wet Granules - Solid Bridges between Particles - Spontaneous Pelletization of "Dry" Powders - Closing Statement - References - Additional Reading
Chapter 6: Electrostatic Charging and Resulting Adhesion.
Voltage Associated with Charge Transfer - Band Theory - The Charging of Organic Solids, Resulting Adhesion - Surface Conductivity - Conclusion - References - Additional Reading
Chapter 7: Mechanical Properties: Stress and Strain, Elastic and Plastic Deformation.
Stress in Solids - Strain - Stress-Strain Relationships - Plastic Deformation, Equivalent Strain - References - Additional Reading
Chapter 8: Area of True Contact and Surface Roughness.
Roughness - Area of Contact and Co/Adhesion Force in Compacts - Conclusions - References